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Quorumpeps®

Quorumpeps® is a resource of quorum sensing signalling peptides. This database is managed by Ghent University. Based upon your input, this search page will give you all information (structure, activity, physicochemical properties and related literature). The database is linked to a manuscript entitled "Quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides", in which the origin of the different peptides and their quorum sensing pathways and methods are described.

Reference:

Sequence, Trivial name, SMILES, Molecular formula, Receptor, Method, Origin, Literature
Peptide
Sequence, Trivial name,
SMILES, Molecular formula The molecular formula is entered using the following template, maintaining the order of the atoms:
CxHxNxOxSx

ERGMT
PhrC
O=C(NC(C(=O)NC(C(=O)O)C(O)C)CCSC)CNC(=O)C(NC(=O)...
C22H41N8O9S1
Receptor List of known receptors

/
AgrC
AgrC1
AgrC2
AgrC3
AgrC4
BlpH
CbaK
CbnK
ComD
ComP
ComR
Cry1Aa
EntK
Fsr
FsrC
LamC
LanK
LuxS
MrsK2
NisK
Npr
PisK
PlcRI
PlcRII
PlcRIII
PlcRIV
PlnB
PltK
PrgX
Rap
RapA
RapC
RapE
RapF
Rgg
Rgg1358
SapK
SilB
SpaK
SppK
SrtK
StbH
StxK
TraA
TRAP
TUP1

AgrC
Origin List of known species

Bacillus anthracis
Bacillus cereus
Bacillus halodurans
Bacillus mojavensis
Bacillus pumilus
Bacillus stearothermophilus
Bacillus subtilis
Bacillus thuringiensis
Carnobacterium maltaromaticum
Carnobacterium piscicola
Clostridium acetobutylicum
Clostridium botulinum
Clostridium sporogenes
Cryptococcus neoformans
Eikenella corodens
Enterococcus faecalis
Enterococcus faecium
Escherichia coli
Lactobacillus plantarum
Lactobacillus sakei
Lactococcus lactis
Pseudomonas aeruginosa
Staphylococcus arlettae
Staphylococcus aureus
Staphylococcus auricularis
Staphylococcus capitis
Staphylococcus caprae
Staphylococcus carnosus
Staphylococcus cochnii subsp. cochnii
Staphylococcus cochnii subsp. urealyticum
Staphylococcus epidermidis
Staphylococcus gallinarum
Staphylococcus intermedius
Staphylococcus lugdunensis
Staphylococcus simulans
Staphylococcus warneri
Staphylococcus xylosus
Streptococcus agalactiae
Streptococcus anginosus
Streptococcus constellatus
Streptococcus crista
Streptococcus dysgalactiae
Streptococcus gordonii
Streptococcus milleri
Streptococcus mitis
Streptococcus mutans
Streptococcus oralis
Streptococcus pneumoniae
Streptococcus pyogenes
Streptococcus sanguis
Streptococcus thermophilus
Streptomyces species
Synthetic
Thermotoga maritima

Species
Staphylococcus aureus
Literature
Author
Title
Year
Journal (full)
Method List of known methods (name)

Absorbance
Gel electrophoresis
HPLC
Neurotoxin assay
Agar diffusion assay
Bacteriocin activity assay
Biofilm assay
Alkaline phosphatase assay
Beta-galactosidase assay
Beta-glucuronidase assay
Beta-lactamase assay
Exopolysaccharideproduction
Fluorescence assay
Gelatinase-inducing assay
Luciferase assay
Microarray
Northern Blotting
Colony counting
Spore assay

Class, Name
Biosensor
Beta-galactosidase

Citation

If you are using or downloading data from the database, please cite "Wynendaele E., Bronselaer A., Nielandt J., D’Hondt M., Stalmans S., Bracke N., Verbeke F., Van De Wiele C., De Tré G. and De Spiegeleer B. Quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides. Nucleic Acids Research 2013, 41 (D1), D655-D659, http://dx.doi.org/10.1093/nar/gks1137"

General Information

- Data submission to Quorumpeps
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- Database schema

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